* {
    margin: 0;
    padding: 0;
    box-sizing: border-box;
    font-family: 'Segoe UI', Tahoma, Geneva, Verdana, sans-serif;
}

body {
    background-color: #f8f9fa;
    color: #333;
    display: flex;
    flex-direction: column;
    min-height: 100vh;
    overflow-x: hidden;
}

/* Header Styles */
.pamphlet-header {
    background: linear-gradient(135deg, #1a237e 0%, #283593 50%, #e53935 100%);
    color: white;
    padding: 80px 0 60px;
    text-align: center;
    box-shadow: 0 4px 12px rgba(0, 0, 0, 0.15);
    position: relative;
    overflow: hidden;
}

.pamphlet-header::before {
    content: "";
    position: absolute;
    top: 0;
    left: 0;
    width: 100%;
    height: 100%;
    background: url('data:image/svg+xml;utf8,<svg xmlns="http://www.w3.org/2000/svg" viewBox="0 0 1440 320"><path fill="%23ffffff" fill-opacity="0.1" d="M0,128L48,144C96,160,192,192,288,186.7C384,181,480,139,576,138.7C672,139,768,181,864,197.3C960,213,1056,203,1152,186.7C1248,171,1344,149,1392,138.7L1440,128L1440,320L1392,320C1344,320,1248,320,1152,320C1056,320,960,320,864,320C768,320,672,320,576,320C480,320,384,320,288,320C192,320,96,320,48,320L0,320Z"></path></svg>');
    background-size: cover;
    background-position: center;
    animation: wave 15s linear infinite;
}

@keyframes wave {
    0% {
        transform: translateX(0);
    }

    50% {
        transform: translateX(-5%);
    }

    100% {
        transform: translateX(0);
    }
}

.pamphlet-header h1 {
    font-size: 48px;
    font-weight: 800;
    margin-bottom: 15px;
    letter-spacing: 1.5px;
    text-transform: uppercase;
    position: relative;
    animation: fadeInDown 1s ease-out;
    text-shadow: 2px 2px 4px rgba(0, 0, 0, 0.2);
}

.pamphlet-header .subtitle {
    font-size: 20px;
    opacity: 0.9;
    font-weight: 300;
    letter-spacing: 0.8px;
    margin-bottom: 20px;
    position: relative;
    animation: fadeInUp 1s ease-out 0.3s both;
    max-width: 700px;
    margin-left: auto;
    margin-right: auto;
    line-height: 1.6;
}

.breadcrumb {
    position: relative;
    margin-top: 20px;
    animation: fadeIn 1s ease-out 0.6s both;
}

.pamphlet-header a {
    display: inline-block;
    font-size: 16px;
    color: #fff;
    opacity: 0.85;
    text-decoration: none;
    transition: opacity 0.3s;
    font-weight: 500;
}

.pamphlet-header a:hover {
    opacity: 1;
}

.pamphlet-header a i {
    margin-right: 8px;
}

/* Animations */
@keyframes fadeInDown {
    from {
        opacity: 0;
        transform: translateY(-30px);
    }

    to {
        opacity: 1;
        transform: translateY(0);
    }
}

@keyframes fadeInUp {
    from {
        opacity: 0;
        transform: translateY(30px);
    }

    to {
        opacity: 1;
        transform: translateY(0);
    }
}

@keyframes fadeIn {
    from {
        opacity: 0;
    }

    to {
        opacity: 1;
    }
}

/* R&D Page Specific Styles */

.rnd-container {
    max-width: 1500px;
    margin: 0 auto;
    padding: 20px;
}

/* Section Styles */
.intro-content {
    display: flex;
    gap: 40px;
    align-items: center;
    border-radius: 10px;
    padding: 20px;
}

.intro-text {
    flex: 1;
}

.intro-text h2 {
    color: #1a237e;
    font-size: 32px;
    font-weight: 700;
}

.intro-text p {
    margin-bottom: 15px;
    line-height: 1.6;
    color: #555;
}

.intro-image {
    flex: 0 0 500px;
}

.image-placeholder {
    background: linear-gradient(135deg, #1a237e 0%, #283593 100%);
    color: white;
    height: 350px;
    border-radius: 10px;
    display: flex;
    flex-direction: column;
    justify-content: center;
    align-items: center;
    text-align: center;
    padding: 20px;
}

.image-placeholder i {
    margin-bottom: 15px;
}

.image-placeholder p {
    font-size: 18px;
    font-weight: 600;
}

/* Section Header */
.section-header {
    text-align: center;
    margin-bottom: 40px;
}

.section-header h2 {
    color: #1a237e;
    font-size: 36px;
    margin-bottom: 15px;
    font-weight: 700;
}

.header-line {
    height: 4px;
    width: 100px;
    background: linear-gradient(90deg, #1a237e 0%, #e53935 100%);
    margin: 0 auto 20px;
    border-radius: 2px;
}

/* Dark Section */
.section-dark {
    background: linear-gradient(135deg, #1a237e 0%, #283593 100%);
    color: white;
    padding: 20px 20px;
    margin-bottom: 30px;
}

.section-dark .section-header h2 {
    color: white;
}

.section-content {
    max-width: 1450px;
    margin: 0 auto;
}

.section-content p {
    text-align: center;
    font-size: 18px;
    line-height: 1.6;
}

/* Strength Grid */
.strength-grid {
    display: grid;
    grid-template-columns: repeat(auto-fit, minmax(250px, 1fr));
    gap: 20px;
    margin-top: 10px;
}

.strength-card {
    background: rgba(255, 255, 255, 0.1);
    border-radius: 10px;
    padding: 20px 20px;
    text-align: center;
    backdrop-filter: blur(10px);
    transition: transform 0.3s ease, box-shadow 0.3s ease;
}

.strength-card:hover {
    transform: translateY(-10px);
    box-shadow: 0 10px 20px rgba(0, 0, 0, 0.2);
}

.strength-icon {
    font-size: 40px;
    color: #e53935;
}

.strength-card h3 {
    font-size: 22px;
    margin-bottom: 15px;
    font-weight: 600;
}

.strength-card p {
    font-size: 16px;
    line-height: 1.5;
    margin: 0;
}

/* Light Section */
.section-light {
    background: white;
    padding: 20px 20px;
    border-radius: 10px;
    margin-bottom: 30px;
    border-left: 5px solid #1a237e;
}

.capabilities-grid {
    display: grid;
    grid-template-columns: repeat(auto-fit, minmax(200px, 1fr));
    gap: 20px;
}

.capability {
    background: white;
    border-radius: 10px;
    padding: 20px 10px;
    text-align: center;
    transition: transform 0.3s ease;
    border: #1a237e solid 1px;
}

.capability:hover {
    transform: translateY(-5px);
}

.capability i {
    font-size: 40px;
    color: #1a237e;
}

.capability h4 {
    font-size: 20px;
    margin-bottom: 10px;
    color: #333;
}

.capability p {
    font-size: 15px;
    color: #666;
    line-height: 1.5;
}

/* Process Development Section */

.key-activities {
    margin-top: 40px;
}

.key-activities h3 {
    color: #1a237e;
    font-size: 24px;
    text-align: center;
    margin-bottom: 20px;
}

.activities-grid {
    display: grid;
    grid-template-columns: repeat(auto-fit, minmax(200px, 1fr));
    gap: 20px;
}

.activity-card {
    background: white;
    border-radius: 10px;
    padding: 25px 20px;
    text-align: center;
    box-shadow: 0 5px 15px rgba(0, 0, 0, 0.05);
    transition: all 0.3s ease;
    border-top: 4px solid #1a237e;
}

.activity-card:hover {
    transform: translateY(-10px);
    box-shadow: 0 10px 25px rgba(0, 0, 0, 0.1);
}

.activity-icon {
    font-size: 40px;
    color: #e53935;
    margin-bottom: 15px;
}

.activity-card h4 {
    color: #1a237e;
    font-size: 18px;
}

.activity-card p {
    color: #666;
    font-size: 14px;
    line-height: 1.5;
}

/* Complex Chemistry Section */
.complex-chemistry {
    padding: 20px 20px;
    border-radius: 10px;
}

.chemistry-expertise {
    display: flex;
    gap: 40px;
    margin-top: 30px;
}

.expertise-list {
    flex: 1;
}

.expertise-list h3 {
    color: #1a237e;
    font-size: 24px;
    margin-bottom: 20px;
}

.expertise-list ul {
    list-style: none;
    margin-bottom: 25px;
}

.expertise-list li {
    margin-bottom: 15px;
    padding-left: 30px;
    position: relative;
    line-height: 1.6;
    color: #555;
}

.expertise-list li i {
    color: #e53935;
    position: absolute;
    left: 0;
    top: 2px;
}

.expertise-list .note {
    background: #e8f4ff;
    padding: 15px;
    border-radius: 5px;
    border-left: 4px solid #1a237e;
    font-style: italic;
    color: #333;
}

.fermentation-box {
    min-height: 310px;
    height: auto;
    flex: 0 0 500px;
    background: white;
    border-radius: 10px;
    padding: 20px;
    box-shadow: 0 5px 15px rgba(0, 0, 0, 0.08);
    border-top: 4px solid #4CAF50;
}

.fermentation-box h3 {
    color: #1a237e;
    font-size: 20px;
    margin-bottom: 20px;
    display: flex;
    align-items: center;
}

.fermentation-box h3 i {
    color: #4CAF50;
    margin-right: 10px;
}

.fermentation-box ul {
    list-style: none;
}

.fermentation-box li {
    margin-bottom: 12px;
    padding-left: 25px;
    position: relative;
    line-height: 1.5;
    color: #555;
}

.fermentation-box li:before {
    content: "•";
    color: #4CAF50;
    font-size: 20px;
    position: absolute;
    left: 0;
    top: -2px;
}

/* Specialized Areas - Main Container */
.specialized-areas {
    width: 100%;
    margin: 0;
    padding: 10px 0 20px;
}

/* Cards Row */
.cards-row {
    display: grid;
    grid-template-columns: repeat(3, minmax(0, 1fr));
    gap: 30px;
}

/* Summary Cards (The 3 boxes in a row) */
.summary-card {
    width: 100%;
    min-width: 0;
    max-width: none;
    background: white;
    border-radius: 12px;
    padding: 20px;
    border-left: 5px solid #e53935;
    cursor: pointer;
    transition: all 0.3s ease;
    position: relative;
    overflow: hidden;
}

.summary-card:hover {
    transform: translateY(-10px);
    box-shadow: 0 15px 30px rgba(0, 0, 0, 0.12);
}

.summary-card.active {
    border-left-color: #1a237e;
    box-shadow: 0 15px 30px rgba(26, 35, 126, 0.15);
}

.card-icon {
    font-size: 40px;
    color: #1a237e;
    margin-bottom: 20px;
    background: #f0f2ff;
    width: 70px;
    height: 70px;
    border-radius: 50%;
    display: flex;
    align-items: center;
    justify-content: center;
    transition: all 0.3s ease;
}

.summary-card.active .card-icon {
    background: #1a237e;
    color: white;
}

.summary-card h3 {
    color: #1a237e;
    font-size: 24px;
    font-weight: 700;
    margin-bottom: 15px;
    line-height: 1.3;
}

.summary-card p {
    color: #666;
    line-height: 1.6;
    margin-bottom: 20px;
}

.card-indicator {
    display: flex;
    align-items: center;
    color: #e53935;
    font-weight: 600;
    font-size: 15px;
}

.card-indicator i {
    margin-left: 8px;
    transition: transform 0.3s ease;
}

.summary-card.active .card-indicator i {
    transform: rotate(180deg);
}

/* Detail Cards (Hidden by default) */
.detail-card {
    display: none;
    background: white;
    border-radius: 12px;
    padding: 20px;
    box-shadow: 0 8px 25px rgba(0, 0, 0, 0.1);
    border-left: 5px solid #1a237e;
    animation: fadeIn 0.5s ease forwards;
    margin-top: 18px;
}

@keyframes fadeIn {
    from {
        opacity: 0;
        transform: translateY(20px);
    }

    to {
        opacity: 1;
        transform: translateY(0);
    }
}

/* Steroid detail animation */
.steroid-detail {
    animation: slideInLeft 0.6s ease forwards;
}

@keyframes slideInLeft {
    from {
        opacity: 0;
        transform: translateX(-30px);
    }

    to {
        opacity: 1;
        transform: translateX(0);
    }
}

/* Oncology detail animation */
.oncology-detail {
    animation: slideInUp 0.6s ease forwards;
}

@keyframes slideInUp {
    from {
        opacity: 0;
        transform: translateY(30px);
    }

    to {
        opacity: 1;
        transform: translateY(0);
    }
}

/* Peptide detail animation */
.peptide-detail {
    animation: slideInRight 0.6s ease forwards;
}

@keyframes slideInRight {
    from {
        opacity: 0;
        transform: translateX(30px);
    }

    to {
        opacity: 1;
        transform: translateX(0);
    }
}

/* Detail card header */
.detail-header {
    display: flex;
    align-items: center;
    margin-bottom: 5px;
}

.detail-icon {
    font-size: 34px;
    color: #1a237e;
    margin-right: 20px;
    background: #f0f2ff;
    width: 70px;
    height: 70px;
    border-radius: 50%;
    display: flex;
    align-items: center;
    justify-content: center;
}

.detail-header h3 {
    color: #1a237e;
    font-size: 32px;
    font-weight: 700;
}

/* Detail content */
.area-content p {
    line-height: 1.6;
    color: #555;
    font-size: 17px;
}

.area-highlight {
    background: #f8f9fa;
    border-left: 4px solid #1a237e;
    padding: 10px;
    margin: 10px 0;
    border-radius: 0 5px 5px 0;
}

.area-highlight h4 {
    color: #1a237e;
    margin-bottom: 10px;
    font-size: 22px;
}

.area-content h4 {
    color: #1a237e;
    font-size: 24px;
}

.area-list {
    margin-top: 10px;
}

.list-item {
    display: flex;
    align-items: flex-start;
    margin-bottom: 15px;
}

.list-item i {
    color: #e53935;
    margin-right: 15px;
    margin-top: 3px;
    font-size: 20px;
}

.list-item span {
    line-height: 1.5;
    color: #555;
    font-size: 16px;
}

/* Integration Box */
.integration-box {
    background: linear-gradient(135deg, #f0f2ff 0%, #e8f4ff 100%);
    border-radius: 10px;
    padding: 20px;
    margin-top: 20px;
}

.integration-box h4 {
    color: #1a237e;
    font-size: 20px;
    margin-bottom: 20px;
    display: flex;
    align-items: center;
}

.integration-box h4 i {
    margin-right: 10px;
    color: #1a237e;
}

.integration-items {
    display: grid;
    grid-template-columns: repeat(auto-fit, minmax(200px, 1fr));
    gap: 20px;
}

.integration-item {
    text-align: center;
    padding: 15px;
    background: white;
    border-radius: 5px;
    box-shadow: 0 3px 8px rgba(0, 0, 0, 0.05);
}

.integration-item i {
    font-size: 30px;
    color: #1a237e;
    margin-bottom: 10px;
}

.integration-item span {
    display: block;
    font-weight: 500;
    color: #333;
}

/* Process Development Box */
.process-development-box {
    background: #fff8f8;
    border-radius: 10px;
    padding: 25px;
    margin-top: 30px;
    border: 1px solid #ffe6e6;
}

.process-development-box h4 {
    color: #1a237e;
    font-size: 20px;
    margin-bottom: 15px;
    display: flex;
    align-items: center;
}

.process-development-box h4 i {
    margin-right: 10px;
    color: #e53935;
}

.process-development-box p {
    margin-bottom: 15px;
    color: #555;
}

.process-development-box ul {
    list-style: none;
}

.process-development-box li {
    margin-bottom: 10px;
    padding-left: 25px;
    position: relative;
    line-height: 1.5;
    color: #555;
}

.process-development-box li:before {
    content: "•";
    color: #e53935;
    font-size: 20px;
    position: absolute;
    left: 0;
    top: -2px;
}

/* Process Optimization */
.process-optimization {
    background: #f0f9ff;
    border-radius: 10px;
    padding: 25px;
    margin-top: 30px;
}

.process-optimization h4 {
    color: #1a237e;
    font-size: 20px;
    margin-bottom: 20px;
    display: flex;
    align-items: center;
}

.process-optimization h4 i {
    margin-right: 10px;
    color: #2196F3;
}

.optimization-grid {
    display: grid;
    grid-template-columns: repeat(auto-fit, minmax(200px, 1fr));
    gap: 20px;
}

.optimization-item {
    text-align: center;
    padding: 20px;
    background: white;
    border-radius: 5px;
    box-shadow: 0 3px 8px rgba(0, 0, 0, 0.05);
}

.optimization-item i {
    font-size: 35px;
    color: #2196F3;
    margin-bottom: 15px;
}

.optimization-item h5 {
    color: #1a237e;
    font-size: 16px;
    margin-bottom: 10px;
}

.optimization-item p {
    color: #666;
    font-size: 14px;
    line-height: 1.4;
}

/* Close button */
.close-detail {
    display: block;
    margin: 30px auto 0;
    padding: 12px 30px;
    background: #1a237e;
    color: white;
    border: none;
    border-radius: 5px;
    font-weight: 600;
    cursor: pointer;
    transition: all 0.3s ease;
    font-size: 16px;
}

.close-detail:hover {
    background: #283593;
    transform: translateY(-2px);
    box-shadow: 0 5px 15px rgba(26, 35, 126, 0.2);
}

/* Infrastructure Section */
.infrastructure-section {
    padding: 20px 20px;
}

.infrastructure-content p {
    text-align: center;
    max-width: 1200px;
    margin: 0 auto 20px;
    font-size: 18px;
    line-height: 1.6;
    color: #555;
}

.infrastructure-grid {
    display: grid;
    grid-template-columns: repeat(auto-fit, minmax(350px, 1fr));
    gap: 30px;
}

.infrastructure-card {
    background: white;
    border-radius: 10px;
    padding: 30px;
    box-shadow: 0 5px 15px rgba(0, 0, 0, 0.08);
    transition: transform 0.3s ease;
}

.infrastructure-card:hover {
    transform: translateY(-5px);
}

.infrastructure-card h3 {
    color: #1a237e;
    font-size: 22px;
    margin-bottom: 20px;
    display: flex;
    align-items: center;
}

.infrastructure-card h3 i {
    margin-right: 10px;
    color: #e53935;
}

.infrastructure-card ul {
    list-style-type: none;
}

.infrastructure-card li {
    margin-bottom: 12px;
    padding-left: 25px;
    position: relative;
    line-height: 1.5;
    color: #555;
}

.infrastructure-card li:before {
    content: "•";
    color: #1a237e;
    font-size: 20px;
    position: absolute;
    left: 0;
    top: -2px;
}

/* Analytical Section */
.analytical-section {
    padding: 0 40px;
}

.analytical-content {
    display: flex;
    gap: 40px;
    align-items: flex-start;
}

.analytical-text {
    flex: 1;
}

.analytical-text p {
    margin-bottom: 20px;
    line-height: 1.6;
    color: #555;
}

.analytical-list {
    margin-top: 30px;
}

.stability-box {
    background: #e8f4ff;
    border-radius: 10px;
    padding: 20px;
    margin-top: 30px;
    border-left: 4px solid #1a237e;
}

.stability-box h4 {
    color: #1a237e;
    font-size: 20px;
    margin-bottom: 15px;
    display: flex;
    align-items: center;
}

.stability-box h4 i {
    margin-right: 10px;
    color: #1a237e;
}

.stability-box p {
    margin-bottom: 15px;
    color: #333;
}

.stability-box ul {
    list-style: none;
}

.stability-box li {
    margin-bottom: 10px;
    padding-left: 25px;
    position: relative;
    line-height: 1.5;
    color: #555;
}

.stability-box li:before {
    content: "•";
    color: #1a237e;
    font-size: 20px;
    position: absolute;
    left: 0;
    top: -2px;
}

.analytical-equipment {
    flex: 0 0 350px;
    background: #f8f9fa;
    border-radius: 10px;
    padding: 30px;
}

.analytical-equipment h3 {
    color: #1a237e;
    font-size: 22px;
    margin-bottom: 20px;
    text-align: center;
}

.equipment-grid {
    display: grid;
    grid-template-columns: repeat(2, 1fr);
    gap: 15px;
}

.equipment-item {
    background: white;
    padding: 15px;
    text-align: center;
    border-radius: 5px;
    font-weight: 600;
    color: #1a237e;
    box-shadow: 0 3px 8px rgba(0, 0, 0, 0.1);
    transition: transform 0.3s ease;
}

.equipment-item:hover {
    transform: translateY(-3px);
    background: #1a237e;
    color: white;
}

.equipment-note {
    margin-top: 20px;
    font-style: italic;
    text-align: center;
    color: #666;
    font-size: 15px;
}

/* Quality by Design Section */
.quality-design {
    padding: 0 40px;
    border-radius: 10px;
    margin-bottom: 10px;
}

.quality-content p {
    text-align: center;
    max-width: 1400px;
    margin: 0 auto 20px;
    font-size: 18px;
    line-height: 1.6;
    color: #555;
}

.quality-grid {
    display: grid;
    grid-template-columns: repeat(auto-fit, minmax(250px, 1fr));
    gap: 20px;
}

.quality-card {
    background: white;
    border-radius: 10px;
    padding: 20px 10px;
    text-align: center;
    box-shadow: 0 5px 15px rgba(0, 0, 0, 0.05);
    transition: transform 0.3s ease;
}

.quality-card:hover {
    transform: translateY(-10px);
}

.quality-icon {
    font-size: 40px;
    color: #1a237e;
    margin-bottom: 20px;
}

.quality-card h4 {
    color: #333;
    font-size: 18px;
    margin-bottom: 5px;
}

.quality-card p {
    color: #666;
    font-size: 14px;
    line-height: 1.5;
    margin: 0;
}

/* Scale-Up Section */
.scaleup-section {
    margin-bottom: 20px;
    padding: 0 40px;
}

.scaleup-list {
    display: grid;
    grid-template-columns: repeat(auto-fit, minmax(200px, 1fr));
    gap: 20px;
}

.scaleup-item {
    background: white;
    border-radius: 10px;
    padding: 10px;
    text-align: center;
    box-shadow: 0 5px 15px rgba(0, 0, 0, 0.05);
    transition: transform 0.3s ease;
    border-top: 4px solid #1a237e;
}

.scaleup-item:hover {
    transform: translateY(-5px);
}

.scaleup-item i {
    font-size: 40px;
    color: #e53935;
    margin-bottom: 15px;
}

.scaleup-item h4 {
    color: #1a237e;
    font-size: 18px;
    margin-bottom: 10px;
}

.scaleup-item p {
    color: #666;
    font-size: 14px;
    line-height: 1.5;
}

/* Sustainability Section */
.sustainability-section {
    margin-bottom: 20px;
    padding: 0 40px;
}

.sustainability-content p {
    text-align: center;
    max-width: 800px;
    margin: 0 auto 20px;
    font-size: 18px;
    line-height: 1.6;
    color: #555;
}

.safety-grid {
    display: grid;
    grid-template-columns: repeat(auto-fit, minmax(250px, 1fr));
    gap: 20px;
}

.safety-card {
    background: white;
    border-radius: 10px;
    padding: 20px;
    text-align: center;
    box-shadow: 0 5px 15px rgba(0, 0, 0, 0.08);
    transition: transform 0.3s ease;
    border: 1px solid #e0e0e0;
}

.safety-card:hover {
    transform: translateY(-10px);
}

.safety-icon {
    font-size: 50px;
    color: #1a237e;
}

.safety-card h3 {
    color: #333;
    font-size: 24px;
    margin-bottom: 5px;
}

.safety-card p {
    color: #666;
    line-height: 1.5;
    margin: 0;
}

/* Collaboration Section */
.collaboration-section {
    padding: 0 40px;
    margin-bottom: 20px;
}

.collaboration-content p {
    text-align: center;
    max-width: 1450px;
    margin: 0 auto 20px;
    font-size: 18px;
    line-height: 1.6;
    color: #555;
}

.collaboration-grid {
    display: grid;
    grid-template-columns: repeat(auto-fit, minmax(250px, 1fr));
    gap: 20px;
}

.collab-card {
    background: white;
    border-radius: 10px;
    padding: 20px;
    box-shadow: 0 5px 15px rgba(0, 0, 0, 0.05);
    transition: transform 0.3s ease;
}

.collab-card:hover {
    transform: translateY(-5px);
}

.collab-card h4 {
    color: #1a237e;
    font-size: 18px;
    margin-bottom: 5px;
    display: flex;
    align-items: center;
}

.collab-card h4 i {
    margin-right: 10px;
    color: #e53935;
}

.collab-card p {
    color: #666;
    font-size: 14px;
    line-height: 1.5;
    margin: 0;
}

/* Section Header */
.section-header {
    text-align: center;
    margin-bottom: 20px;
}

.section-header h2 {
    font-size: 36px;
    color: #1a237e;
    margin-bottom: 10px;
}

.header-line {
    width: 80px;
    height: 4px;
    background: #e53935;
    margin: 0 auto;
    border-radius: 2px;
}

/* Strength Summary */
.strength-summary {
    padding: 0 20px;
}

/* Grid Layout */
.strength-list {
    max-width: 1500px;
    margin: 0 auto 20px;

    display: grid;
    grid-template-columns: repeat(2, 1fr);
    /* Two points per row */
    gap: 15px;
}

/* Strength Item Card */
.strength-item {
    display: flex;
    align-items: flex-start;
    padding: 18px 20px;
    background: white;
    border-radius: 8px;
    transition: all 0.3s ease;
}

.strength-item:hover {
    background: #eef2ff;
    transform: translateY(-3px);
}

/* Icon */
.strength-item i {
    color: #e53935;
    margin-right: 15px;
    margin-top: 4px;
    font-size: 20px;
}

/* Text */
.strength-item span {
    font-size: 18px;
    line-height: 1.5;
    color: #333;
}

/* Conclusion Box */
.conclusion-box {
    background: linear-gradient(135deg, #1a237e 0%, #283593 100%);
    color: white;
    padding: 30px;
    border-radius: 12px;
    text-align: center;
    max-width: 1500px;
    margin: 0 auto;
}

.conclusion-box p {
    font-size: 20px;
    line-height: 1.6;
    margin: 0;
}


/* Responsive Design */
@media (max-width: 992px) {
    .intro-content {
        flex-direction: column;
    }

    .intro-image {
        flex: 0 0 auto;
        width: 100%;
        max-width: 400px;
        margin: 0 auto;
    }

    .chemistry-expertise {
        flex-direction: column;
    }

    .fermentation-box {
        flex: 0 0 auto;
        width: 100%;
        min-height: 0;
    }

    .analytical-content {
        flex-direction: column;
    }

    .analytical-equipment {
        flex: 0 0 auto;
        width: 100%;
    }

    .infrastructure-grid {
        grid-template-columns: 1fr;
    }

    .cards-row {
        grid-template-columns: 1fr;
        gap: 16px;
    }
}

@media (max-width: 768px) {
    .rnd-container {
        padding: 16px 12px;
    }

    .intro-content,
    .section-dark,
    .section-light,
    .complex-chemistry,
    .area-card,
    .infrastructure-card,
    .analytical-equipment,
    .safety-card,
    .quality-design,
    .collaboration-section,
    .quality-card,
    .scaleup-item,
    .collab-card {
        padding: 25px 20px;
    }

    .section-header h2 {
        font-size: 28px;
    }

    .intro-text h2 {
        font-size: 26px;
    }

    .area-header h3 {
        font-size: 24px;
    }

    .equipment-grid {
        grid-template-columns: repeat(2, 1fr);
    }

    .strength-grid,
    .capabilities-grid,
    .activities-grid,
    .safety-grid,
    .quality-grid,
    .scaleup-list,
    .collaboration-grid {
        grid-template-columns: 1fr;
    }

    .integration-items,
    .optimization-grid {
        grid-template-columns: 1fr;
    }

    .fermentation-box {
        padding: 16px;
        border-radius: 10px;
        min-height: 0;
    }

    .fermentation-box h3 {
        font-size: 18px;
        line-height: 1.35;
        margin-bottom: 12px;
    }

    .fermentation-box h3 i {
        margin-right: 8px;
        font-size: 18px;
    }

    .fermentation-box li {
        font-size: 14px;
        line-height: 1.45;
        margin-bottom: 8px;
        padding-left: 20px;
    }

    .specialized-areas {
        padding: 8px 0 16px;
    }

    .summary-card {
        padding: 16px;
        border-left-width: 4px;
    }

    .summary-card h3 {
        font-size: 20px;
        margin-bottom: 10px;
    }

    .summary-card p {
        font-size: 14px;
        margin-bottom: 14px;
        line-height: 1.5;
    }

    .card-icon {
        width: 56px;
        height: 56px;
        font-size: 26px;
        margin-bottom: 12px;
    }

    .detail-card {
        padding: 14px;
        margin-top: 12px;
        border-left-width: 4px;
    }

    .detail-header {
        gap: 10px;
        margin-bottom: 10px;
    }

    .detail-icon {
        width: 50px;
        height: 50px;
        font-size: 22px;
        margin-right: 0;
        flex-shrink: 0;
    }

    .detail-header h3 {
        font-size: 22px;
        line-height: 1.3;
    }
}

@media (max-width: 480px) {
    .pamphlet-header h1 {
        font-size: 36px;
    }

    .section-header h2 {
        font-size: 24px;
    }

    .area-header {
        flex-direction: column;
        text-align: center;
    }

    .area-icon {
        margin-right: 0;
        margin-bottom: 15px;
    }

    .equipment-grid {
        grid-template-columns: 1fr;
    }

    .rnd-container {
        padding: 12px 8px;
    }

    .summary-card h3 {
        font-size: 18px;
    }

    .detail-header h3 {
        font-size: 19px;
    }

    .area-content p,
    .list-item span {
        font-size: 14px;
    }

    .fermentation-box {
        padding: 12px;
    }

    .fermentation-box h3 {
        font-size: 16px;
    }

    .fermentation-box li {
        font-size: 13px;
    }
}